SPPIDER
S
olvent accessibility based
P
rotein-
P
rotein
I
nterface
i
DE
ntification and
R
ecognition
Type of query
(1) Prediction of interaction sites using a structure of a
single protein chain
(2) Analysis of known
protein-protein complexes
and identification of interfaces
Query options
(1) Prediction of interaction sites based on a single protein chain (
Help
)
Query
PDB code
OR
PDB file
Chain label
(optional)
Get PDB code by keyword
SPPIDER settings
Version
SPPIDER I
SPPIDER II
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1.0
Tradeoff
between
Sensitivity
and
Specificity
Output
E-Mail address
(optional)
Generate PDB file
with prediction encoded by B-factors as
Classification
Regression
Add information about known interactions
by
Adding to
Contrasting with
prediction
(Not fully tested!)
Add solvent accessibility prediction results
(from SABLE)
to e-mail message
In
CASP
format
(2) Interface identification within known protein-protein complexes (
Help
)
PDB code
considered as
Asymmetric
unit
PQS-based
biological
unit
Get PDB code by keyword
PDB file
RSA change threshold
Absolute (Ų)
Relative (%)
Output
As summary
Each interface separately
E-Mail address
(optional)
(3) Interfacial residues prediction from amino acid sequence (
Help
)
Sequence name
(optional)
Amino acid sequence
(one letter code)
FASTA file
Our group
Contact us
About SPPIDER
Statistics
News
Credits
The SPPIDER protein interface recognition server was developed by
A.Porollo
and
J.Meller